Taking Benadryl With Klonopin: Benadryl is an over-the-counter medicine that is commonly used to treat seasonal allergy-related symptoms. This drug contains the generic chemical Diphenhydramine Hydrochloride (DPH), which has significant sedative and drowsy effects in addition to treating symptoms of seasonal allergies.
Similarly, Klonopin can have dose-dependent effects on eyesight, attention, responsiveness, alertness, and reaction time. As a result, the patient experiences weariness, somnolence, and generalized impairment of cognition as a result of the interaction between Klonopin and Benadryl. This can be especially risky and lead to accidents if occupations requiring mental acuity and motor dexterity, such as driving or operating machinery, are performed while taking these drugs.